GT Repeats Are Associated with Recombination on Human Chromosome 22

Table 1.

GT Repeat Density Versus Recombination Intensity

Intermarker interval Sex-averaged Female-specific Male-specific
GT repeat density (repcats/Mb) recombination intensity (cM/Mb) GT repeat density (repeats/Mb) recombination intensity (cM/Mb) GT repeat density (repeats/Mb) recombination intensity (cM/Mb)
D22S427 443 1.95 443 2.24 443 1.43
D22S446 418 1.98 418 3.58 418 0.44
D22S1174 655 1.32 655 1.98 680 0.59
D22S1164 936 2.80 936 5.60
D22S429 1224 4.51 1224 1.89 1224 7.09
D22S1154 1524 3.31 1524 1.26 1524 6.54
D22S1167 752 4.21 752 3.39 807 3.35
D22S1144 1050 3.71 564 0.26
D22S1163 547 0.13 547 0.26
D22S275 723 4.31 723 4.39 723 4.23
D22S273 562 1.15 568 0.76 562 0.75
D22S1172 530 0.58 530 1.16
D22S1158 627 1.37 627 3.18
D22S1147 717 0.55 717 3.14
D22S1152 553 2.23 553 2.64 553 0.63
D22S424 1828 3.76 1828 4.52 735 0.25
D22S278 1763 6.96 1763 14.1
D22S1173 442 7.00 442 14.2
D22S283 1348 8.09 1348 16.5
D22S692 1909 3.39 1909 6.94
D22S1045 400 1.79 400 3.68
D22S1156 340 2.13 340 4.43
D22S272 675 0.46 675 0.96
D22S423 338 0.48 338 0.97
D22S1157 627 0.40 627 0.83
D22S1171 1250 3.36 1250 3.38 1250 3.07
D22S1159 2032 3.50 2032 1.74 1754 4.48
D22S1153 131 5.13 432 0.88
D22S928 338 1.63 472 1.55
D22S1149 480 0.80 480 0.99
D22S1170 1655 6.45 1655 2.01 1655 11.2
D22S922 2870 8.58 2870 8.58 2870 13.1
D22S1169
  • The interval is defined between the marker in each row and the following marker. For example, the data in the first row refers to the D22S427–D22S446 interval. For the sex-specific data, some intervals contain no recombination data (no recombinants detected). The values in those cells have been averaged with adjacent intervals. For example, D22S273–D22S1152 is considered a single interval in the female-specific columns.

This Article

  1. Genome Res. 10: 1108-1114

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