Scatter plots showing the genotype assignment at 31 mutant sites for 192 samples from known mutation carriers, homozygous patients, and unknown individuals. The acronyms for the diseases above each scatter-plot are as explained in the Figure 2A legend. The ratios between the signal intensities from the normal and mutant allele-specific reactions are given on the y-axis. The ratios are near the value 1 in heterozygotes, elevated in normal homozygotes, and reduced in mutant homozygotes. The x-axis shows the signal intensities from each sample after correction for the average local background signal from the arrays. The red asterisks in the heterozygote clusters indicate that synthetic templates were analyzed because no carrier samples were available.
