Table 2.
Average Nonsynonymous (Ka) and Synonymous (Ks) Substitution Rate in Orthologous Genes Between Human and Murids According to their Number of Pseudogenes
| No. of retropseudogenes | Ka | Ks | Ks_nd |
| 0 (n = 349) | 0.109 ± 0.095 | 0.519 ± 0.149 | 0.396 ± 0.103 |
| 1 (n = 96) | 0.044 ± 0.063 | 0.470 ± 0.241 | 0.421 ± 0.236 |
| 2 (n = 22) | 0.022 ± 0.042 | 0.470 ± 0.134 | 0.436 ± 0.099 |
| ≥3 (n = 13) | 0.026 ± 0.045 | 0.437 ± 0.135 | 0.399 ± 0.13 |
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Rate according to no. of pseudogenes = mean value ±s.d. Ks_nd:Ks computed after removing doublet substitutions (see Duret and Mouchiroud 2000). The number of genes is indicated for each sample.











