
Illustration of the effects of Single coverage.The β-globin gene clusters of human (GenBank entry HUMHBB) and chicken (GenBank entry CHKHBBRE) were aligned. Because there are six genes in human and four in chicken (A), the chaining option would leave two of the human genes unaligned (B). However, a dot plot made with the Single coverage option shows all human regions having matches in the chicken sequence, with no duplicate matches (C).











