PipMaker—A Web Server for Aligning Two Genomic DNA Sequences

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

Illustration of the effects of chaining. The pro-α1 type II collagen loci of humans (GenBank accession no. HUMCOL2A1Z) and mice (GenBank entry MUSPACOLL) were aligned. With PipMaker defaults, exon duplications produce redundant matches in the pip and dot plot (A,B), which are eliminated by the chaining option (C,D).

This Article

  1. Genome Res. 10: 577-586

Preprint Server