Figure 1.
A GHMM including frame constraints. (B) The beginning state; (J5′) the 5′ UTR content sensor; (S) the start codon signal sensor; (EI) the initial exon content sensor; (D) the 5′ splice site sensor; (A) the 3′ splice site sensor; (E) the internal exon content sensor; (I) the intron content sensor; (EF) the final exon content sensor; (T) the start codon signal sensor; (F) the end state. (ES) The single exon gene content sensor. For multiple genes in genomic regions such as Adh, an additional arc loops from F to B and models the intergenic region including the promoter sensor.
