Using Database Matches with HMMGene for Automated Gene Detection in Drosophila

Table 3.

The Performance on the std3 Set

No database matches All but EST matches Including all matches Predictions >200 Original submission
Base level
 Sensitivity 74.0 80.6 81.1 81.1 77.9
 Specificity 91.3 92.5 91.1 91.5 90.7
Exon level
 Sensitivity 48.3 50.4 51.4 51.4 50.1
 Specificity 58.1 56.7 52.7 54.5 53.2
 Missing exons 29.8 24.2 23.1 23.1 25.6
 Wrong exons 15.6 15.1 21.3 18.7 20.9
Gene level
 Sensitivity 100% 26.1 28.8 30.2 30.2 29.3
 Sensitivity 99% 28.8 32.0 33.3 33.3 32.4
 Sensitivity 95% 33.3 39.2 42.3 42.3 41.4
 Specificity 100% 34.3 33.9 30.2 32.4 30.4
 Specificity 99% 37.9 37.6 33.3 35.7 33.6
 Specificity 95% 43.8 46.0 42.3 45.4 43.0
 Missing genes 16.7 9.9 9.9 9.9 13.2
 Wrong genes 7.7 6.9 16.7 10.6 16.4
  • In the column Predictions >200, 15 predicted genes with a coding region <200 bp long were removed from the predictions using all database matches. Other columns correspond to Table 2.

This Article

  1. Genome Res. 10: 523-528

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