New Target Regions for Human Hypertension via Comparative Genomics

Table 2.

Predicted Chromosomal Segments in the Human Genome Based on Synteny to Blood Pressure QTLs in the Rat

graphic
  • Genetic markers and candidate genes provided represent markers, as mapped and listed in GeneMap98. Homologous regions are listed in relation to the respective genetic location in the rat, and putative candidate genes were chosen based on MIM-Maps and verified for map position in the syntenic region in mouse/rat using the MGD. Of 67 QTLs, 64 were converted to discrete homologous regions in the human genome; 3 QTLs (QTLs 43, 44, and 50) could not be converted because of incomplete coverage of the rat genetic map or lack of homologous genes being mapped between rat, mouse, and human.

This Article

  1. Genome Res. 10: 473-482

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