Construction of a High-Resolution 2.5-Mb Transcript Map of the Human 6p21.2–6p21.3 Region Immediately Centromeric of the Major Histocompatibility Complex

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.Figure 2.Figure 2.
Figure 2.

Identification of the BR140-2 and the human CUTA1genes by cDNA selection. (A)The overlap between the translated (ORF1) cDNA clone 1.3/C11 and peregrin shows that 1.3/C11 shares the same cysteine (C) and histidine (H) (both underlined) residues with peregrin, which are involved in the formation of the zinc fingers of peregrin. Bullets denote identity and vertical lines similarity (also for B and C). (B)

The overlap between the translated (ORF2) cDNA clone 4.3/G11 and peregrin shows that clone 4.3/G11 contains a domain highly similar to the bromodomain of peregrin. (C) The overlap between the translated (ORF3) of ntcon6 and two CutA protein sequences forEscherichia coli and Arabidopsis thaliana are shown. The percentage of identity and similarity between each sequence is shown under I and S, respectively, at the bottom right.

This Article

  1. Genome Res. 10: 454-472

Preprint Server