Frequent Human Genomic DNA Transduction Driven by LINE-1 Retrotransposition

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Figure 1.
Figure 1.

L1-driven 3′ transduction. Incorporation of additional (3′ flanking) sequence into the transcript generated from the L1 promoter is followed by reverse transcription and integration of this longer cDNA into new genomic loci. (Ovals) Target site duplications; (purple arrows) polyadenylation signals (weak and strong); (AAAn) poly(A) tail.

This Article

  1. Genome Res. 10: 411-415

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