A Fast and Scalable Radiation Hybrid Map Construction and Integration Strategy

Table 1.

Average Number of Chromosome Breaks Between Consecutive Markers and the Average of the Logarithm of Two-Point Likelihood for the Maps with Breakage Probabilities Computed as in Extended TSP + MLE

Chr OCB/no. of markers Log [L(M)]/no. of markers
Whitehead RHMAPPER CONCORDE Whitehead RHMAPPER CONCORDE
 1 3.70 ? 1.66 −5.74 ? −2.28
 2 4.18 3.80 2.12 −6.37 −5.47 −3.02
 3 3.92 2.71 1.97 −6.17 −4.22 −2.82
 4 3.84 3.75 2.15 −5.97 −5.37 −3.01
 5 3.66 3.37 1.99 −5.72 −4.98 −2.73
 6 3.59 2.60 1.70 −5.73 −4.07 −2.44
 7 4.00 2.86 1.92 −6.20 −4.41 −2.79
 8 3.64 3.64 2.09 −5.88 −5.39 −2.97
 9 3.56 2.86 1.85 −5.59 −4.28 −2.55
10 3.76 3.55 2.04 −5.95 −5.24 −2.91
11 3.35 2.53 1.86 −5.26 −3.87 −2.42
12 3.67 3.87 1.98 −5.86 −5.66 −2.81
13 3.58 2.92 2.01 −5.72 −4.50 −2.89
14 3.43 2.43 1.79 −5.52 −3.78 −2.53
15 4.28 4.16 2.25 −6.64 −5.99 −3.19
16 4.43 3.18 2.32 −6.70 −4.87 −3.30
17 4.27 2.74 2.03 −6.71 −4.29 −2.83
18 4.22 3.07 2.47 −6.48 −4.76 −3.63
19 4.40 2.78 1.99 −6.74 −4.26 −2.67
20 3.76 2.41 1.74 −6.10 −3.83 −2.45
21 3.99 2.64 2.19 −6.65 −4.40 −3.35
22 4.12 2.87 2.17 −6.62 −4.53 −3.09
X 3.37 2.36 1.70 −5.22 −3.61 −2.32
  • (Chr) Chromosome number; (Whitehead) Whitehead Institute map (Hudson et al., 1995); (RHMAPPER) maps computed by us using RHMAPPER for GB4 panel data; (CONCORDE) maps computed using CONCORDE for GB4 panel data.

This Article

  1. Genome Res. 10: 350-364

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