Evolution of the Neuropeptide Y Receptor Family: Gene and Chromosome Duplications Deduced from the Cloning and Mapping of the Five Receptor Subtype Genes in Pig

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1.
Figure 1.

A phylogenetic tree for the porcine, mouse, and human NPY receptor sequences from transmembrane 1 to transmembrane 7 without the third intracellular loop (252–258 amino acids in total). The sequences were aligned using the CLUSTAL method and the tree constructed using the neighbor-joining method with the Caenorhabditis elegans NPY receptor-like sequence (GenBank accession no. AAA93419) as the outgroup. The strength of the tree topology was tested by bootstrap analysis with 1000 replications; the values are shown above each branch.

This Article

  1. Genome Res. 10: 302-310

Preprint Server