Detection of Deleted Genomic DNA Using a Semiautomated Computational Analysis of GeneChip Data

Table 2.

Deletion Screen of BCG Pasteur Shows that TSTEP/Deletion Assembly Finds Known Deletions plus Three New Deletions

Complete TSTEP/deletion assembly results for screen of BCG Pasteur RD number Sequencing confirmation results
Start End Length No. of probe pairs Proportion of probe pairs above the cutoff pvalue
Confirmation result Start End Length
264681 266633 1953 35 0.03 RD4 Deletion 264752 266658 1907
1058107 1058601 495 16 0.19 Present
1333051 1334446 1396 29 0.03 N-RD18 Deletion 1332920 1334466 1547
1402897 1405631 2735 51 0.08 RD10 Deletion 1402932 1405939 3008
1483164 1483836 673 13 0.15 Present
1695829 1708776 12948 430 0.04 RD6 Deletion 1696017 1708750 12734
1779216 1789408 10193 380 0.03 RD3 Deletion 1779276 1788525 9250
1998716 2007316 8601 210 0.02 RD14 Deletion 1998225 2007297 9073
2196766 2197597 832 23 0.09 Present
2208107 2231883 23777 705 0.06 RD2, RD15 Deletion 2208003 2231848 23846
2329435 2332234 2800 58 0.05 RD12 Deletion 2330073 2332104 2032
2626662 2637681 11020 271 0.04 RD7 Deletion 2626070 2635032 8963
2969694 2980802 11109 310 0.07 RD13 Deletion 2969988 2981195 11208
3485154 3487575 2422 98 0.05 RD5 Deletion 3484737 3487512 2776
3842882 3846520 3639 119 0.05 RD11 Deletion 3842653 3847540 4888
3896832 3897792 961 27 0.11 N-RD17 Deletion 3897069 3897783 715
4056690 4062741 6052 108 0.03 RD9 Deletion 4056837 4062732 5896
4188975 4190798 1824 29 0.17 N-RD25 Deletion 4189605 4190757 1153
4349983 4359538 9556 127 0.03 RD1 Deletion 4350262 4359720 9459
  • (TSTEP) Tandom Set Terminal Extreme Probability.

  • After the deletion naming convention in Behr et al. (1999). New deletions are indicated with N-RD.

This Article

  1. Genome Res. 10: 2044-2054

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