Table 2.
Identification of New T. cruzi Genes
| dbGSS | Description | Score | Expect |
| 11462 | ref-NP_011059.1-GLC7-protein phosphatase type I [Saccharomyces cereviseae] | 474 | 0.00E+00 |
| 10993 | sp-P22679-elongation factor TU (EF-TU) [Mycoplasma hominis] | 312 | 0.00E+00 |
| 00184 | sp-P46794-cystathionine beta-synthase [Dictyostelium discoldeum] | 303 | 0.00E+00 |
| 11438 | sp-O76767-lumen protein retaining receptor [Drosophila melanogaster] | 208 | 0.00E+00 |
| 11472 | emb-CAB56598.1-alpha dynein heavy chain [Chlamydomonas reinhardtii] | 202 | 0.00E+00 |
| 11026 | gi-2425121-Spalten [Dictyostelium discoldeum] | 116 | 0.00E+00 |
| 12036 | gb-AAF19802.1-N-myristoyl transferase [Brassica oleracea] | 107 | 0.00E+00 |
| 01761 | gl-3004644-trypanothione synthetase [Crithidia fasciculata] | 428 | 5.00E-42 |
| 11137 | gb-AAB67249.1-T-complex protein 1, Beta subunit [Homo sapiens] | 424 | 9.00E-42 |
| 11193 | ref-NP_014850.1-RET1-second-largest subunit of RNA polymerase III [Saccharomyces cereviseae] | 422 | 1.00E-41 |
| 11590 | gb-AAF08387.1-26S proteasome regulatory complex subunit p48A [Drosophila melanogaster] | 419 | 2.00E-41 |
| 11120 | emb-CAA65384-malate dehydrogenase [Mesembryanthemum crystallinum] | 371 | 2.00E-35 |
| 11285 | gi-1931649-DNA helicaso isolog [Arabidopsis thaliana] | 353 | 2.00E-33 |
| 11563 | ref-NP_013458.1-transaldolase [Saccharomyces cerevisiae] | 348 | 7.00E-33 |
| 09938 | gi-2246458-S-adenosyl-methionine-sterol-C-methyltransferase [Ricinus communis] | 348 | 8.00E-33 |
| 0705 | pir-T1017324-sterol C-methyltransferase-castor bean [Ricinus communis] | 348 | 9.00E-33 |
| 11338 | gb-AAC02737.1-3-hydroxyisobutyryl-coenzyme A hydrolase [Arabidopsis thaliana] | 341 | 5.00E-32 |
| 11467 | gb-AAF04493.1-acetyl-CoA carboxylase 1 [Toxoplasma gondii] | 330 | 7.00E-31 |
| 10956 | dbj-BAA84364.1-DEIH-box RNA/DNA helicase [Arabidopsis thaliana] | 328 | 2.00E-30 |
| 11575 | gb-AAC73040.1-putative AAA-type ATPase [Arabidopsis thaliana] | 323 | 5.00E-30 |
| 11516 | sp-P05439-ATP synthase alpha chain [Rhodobacter blasticus] | 319 | 2.00E-29 |
| 11606 | sp-P51044-citrate synthase, mitochondrial precursor [Aspergillus niger] | 321 | 2.00E-28 |
| 11417 | gb-AAF21464.1-proline oxidase 2 [Homo sapiens] | 310 | 2.00E-28 |
| 11502 | gi-2654103-MAPKK kinase [Neurospora crassa] | 304 | 9.00E-28 |
| 11523 | gb-AAD26855.1-phenylalanyl tRNA synthetase beta subunit [Mus musculus] | 301 | 2.00E-27 |
| 11568 | gi-4101722-histone deacetylase mHDA1 [Mus musculus] | 301 | 2.00E-27 |
| 11480 | gi-2462752-phosphatidylinositol 3-kinase [Arabidopsis thaliana] | 299 | 4.00E-27 |
| 11463 | sp-P32826-serine carboxypeptidase precursor [Arabidopsis thaliana] | 299 | 4.00E-27 |
| 10965 | gi-687208-dynein heavy chain isotype 5C [Tripneustes gratilla] | 289 | 5.00E-26 |
| 11328 | pir-A56220-protein kinase aurora-fruit fly [Drosophila melanogaster] | 287 | 1.00E-25 |
| 11446 | sp-O15228-dihydroxyacetone phosphate acyltransferase (DAP-AT) [Homo sapiens] | 280 | 7.00E-25 |
| 11433 | gb-AAF11511.1-acetyl-CoA acetyltransferase [Deinococcus radiodurans] | 279 | 9.00E-25 |
| 11601 | sp-P30575-enolase 1 (2-phosphoglycerate dehydratase) [Candida albicans] | 278 | 1.00E-24 |
| 01810 | sp-O94476-eukaryotic translation initiation factor 6 (EIF-6) [Schizosaccharomyces pombe] | 275 | 3.00E-24 |
| 0740 | gb-AAF62506.1-ribosomal protein LS [Trypanoplasma borreli] | 273 | 5.00E-24 |
| 11274 | pir-S70896-aminomethyltransferase [Saccharomyces cerevisiae] | 271 | 5.00E-24 |
| 11279 | gi-780410-helicase [African swine fever virus] | 272 | 6.00E-24 |
| 11882 | sp-Q07405-ATP synthase alpha chain [Myxococcus xanthus] | 269 | 1.00E-23 |
| 11432 | emb-CAB40791.1-centrin [Euplotes octocarinatus] | 265 | 3.00E-23 |
| 11654 | gi-1872473-delta-24-sterol methyltransferase [Triticum aestivum] | 258 | 7.00E-23 |
| 01015 | pir-A56492-protein kinase ERK2 [Dictyostelium discoideum] | 280 | 8.00E-23 |
| 11584 | ref-NP_005678.1-phenylalanyl-tRNA synthetase beta-subunit [Homo sapiens] | 259 | 1.00E-22 |
| 11434 | sp-O05593-methionyl-tma synthetase [Mycobacterium tuberculosis] | 254 | 6.00E-22 |
| 11038 | gi-1354084-axonemal dynein light chain p33 (Strongylocentrotus purpuratus] | 251 | 2.00E-21 |
| 11440 | gi-2665637-mismatch repair protein MSH6 [Mus musculus] | 248 | 4.00E-21 |
| 11248 | gb-AAF22155.1-ARD-1 N-acetyltransferase homologue [Mus musculus] | 244 | 1.00E-20 |
| 11852 | gb-AAC32590.1-sperm flagellar protein Repro-SA-1 [Homo sapiens] | 239 | 5.00E-20 |
| 01825 | dbj-BAA20996-kinesin-like protein [Caenorhabditis elegans] | 239 | 6.00E-20 |
| 11210 | pir-A35630-regulatory protein algR3 [Pseudomonas aeruginosa] | 237 | 7.00E-20 |
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GSS sequences were used to search NCBI's non-redundant database using BLASTX. The first 50 GSSs out of the 947 GSSs showing matches against non-T. cruzi sequences are listed. Detailed information about the homologies found for GSSs can be found athttp://www.iib.unsam.edu.ar/genomelab/tcruzi/gss.html.
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↵GSS names in dbGSS are the numbers given here preceded by GSSTc (e.g., GSSTc11210).
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↵Descriptions are taken directly from the BLAST reports.
