Genetic linkage map of the zebrafish genome. The positions of 2119 polymorphic markers mapped in the heat shock (HS) panel are shown. Genes and expressed sequence tags (ESTs) with identified human orthologs are color coded according the chromosomal position of the human gene. Gene names are shown in bold type. According to zebrafish convention (http://zfin.org/zf_info/nomen.html), ESTs with putative human orthologs are named according to their human counterparts. Other ESTs are named by their GenBank accession numbers. Simple-sequence length polymorphism names begin with “Z” or “GOF”, following the nomenclature of Shimoda et al. (1999). This map reports revised positions for three genes, tbx6,isl3, and six7, that were assigned to different locations in previous maps (Postlethwait et al. 1998; Geisler et al. 1999; Kelly et al. 2000). In addition, we have revised two previous assignments (Kelly et al. 2000) for ESTs, and we have removed from the dataset eight ESTs that were originally mapped in the HS panel because of discrepancies detected in repeat genotype assays. Sequence comparisons of the ESTs mapped in the HS panel by Kelly et al. (2000)revealed 14 cases in which two different ESTs that were likely to correspond to different regions of the same gene were mapped to the identical positions. We have removed one member of each of these putative duplicate pairs from the dataset.
