Physical maps of DNA markers on chromosome 7 in Candida albicans strain 1006. DNA markers and restriction maps: The original maps were reported by Chibana et al. (1998). DNA markers used in this study are shown on the top. Fragments 7A, 7F, and 7G are separated by MRSs that include SfiI sites. Fragments 7C and 7A are separated by an SfiI site that is not in an MRS. The two MRSs are inverted and flanking SfiI fragment 7F. OnlyXhoI sites adjacent to MRS are shown. The MRS region between 7A and 7F was magnified to show the order of subrepeat elements RB2, RPS and HOK (a). Minimal fosmid contig: The minimal contig is composed of the minimum number of fosmids covering the entire chromosome 7. The minimal contig was divided into three contigs, 7C–7A, 7F, and 7G, separated by the two MRS sequences, to identify the distribution of chromosome 7 elements among the different strains. The fosmids from 6F1 to 13A7 were used as the 7C–7A contig, those from 15H9 to 13E11 as the 7F contig, and those from 16H4 to 34B3 as the 7G contig. Fosmids 11G4, 11B11, 19E1, and 18B6 include subtelomeric repeats 9F4, 4H5, and 8B4 include the MRS (b).
