Table 5.

Chromosomal Location

Species	Locus	References	Centromere—gene order—telomere
H	14q32.1	a	α₁-antichymotrypsin ∣ protein C Inhibitor ∣ kallistatin ∣ α₁-antitrypsin ∣ α₁-antitrypsin-related ∣ corticosteroid binding globulin
H	1q41–qter	bA	Angiotensinogen
H	1q23–q25.1	c	Antithrombin III
H	2q33–q35	dG	Glia-derived nexin
H	22q11.2	e	Heparin cofactor II
H	11q13.5	f	Heat shock protein 47
H	18q21.3	g	Maspin ∣ Squamous Cell Carcinoma Antigen-2 ∣ Squamous Cell carcinoma Antigen-I ∣ Plasminogen Activator Inhibitor-2 ∣ Bomapin ∣ PI-8
H	3q26	h	Neuroserpin
H	7q21.3–q22	i	Plasminogen Activator Inhibitor-1
H	17p13.3	j	Pigment epithelium-derived factor
H	6p25	k	PI-6 ∣ PI-9 ∣ Monocyte neutrophil elastase inhibitor
H	Xq21–q22	l	thyroxine-binding globulin
M	1	d	Glia-derived nexin
M	1 (Bcl2)	m	Squamous Cell Carcinoma Antigen-2
M	13	n	SPI-6 ∣ SPI-3
S	2	d	Glia-derived nexin
C	∼V-20.61	o	AAB71270 ∣ AAB71272
C	V 0.68		AAB52317 ‖ AAB52318
C	V 0.88		AAB37049 ∣ AAB37055
C	V 10.48		2706568
	M01G12
C	V13.54		CAB04071
A	I mi291a	p	AAD46018
	69cM
A	I mi424		AAC27146
	90cM
A	II mi398		AAD15462
	29cM
A	II GPA1		AAD23667
	48cM
A	II B68 50cM		AAC14489
A	II ve016		AAC36162 ∣ AAC36163 ∣ AAC36164
	67cM
A	I (clone F19K23)		AAB60763

For mammalian serpins, we relied on LocusLink (Pruitt et al. 2000) and the primary literature. For genes identified in genome projects, we report the chromosomal location of the clone of origin, where possible. (H) human; (M) mouse; (S) sheep; (C) Caenorhabditis elegans;(A) Arabidopsis thaliana.
Rollini and Fournier 1997; ^b Kageyama et al. 1984;^c Bock et al. 1985; ^d Carter et al. 1995;^e Herzog et al. 1991; ^f Ikegawa and Nakamura 1997;^g Silverman et al. 1998; ^h Schrimpf et al. 1997;ⁱ Klinger et al. 1987; ^j Goliath et al. 1996;^k Sun et al. 1997; ^l Flink et al. 1986;^m Bartuski et al. 1998; ⁿ Sun et al. 1997; C. elegans Sequencing Consortium 1998;^p http://www.arabidopsis.org.

Phylogeny of the Serpin Superfamily: Implications of Patterns of Amino Acid Conservation for Structure and Function