Detecting Gene Copy Number Fluctuations in Tumor Cells by Microarray Analysis of Genomic Representations

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Figure 5.
Figure 5.

Simulations of microarray analysis of 10,000 probes where 20 probes are amplified fourfold and 20 probes are homozygously deleted. Either hybridization of BglII representations (A) or hybridization of total DNA (B–D) were modeled. The hybridization of total genomic DNA (B) also was modeled by moving averages of four (C) or replica measurements of four (D).

This Article

  1. Genome Res. 10: 1726-1736

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