Sequence and Comparative Analysis of the Mouse 1-Megabase Region Orthologous to the Human 11p15 Imprinted Domain

Table 6.

CpG Island Organization and Allelic Expression

Gene Expressed allele CpG island 1 location CpG island 2 location CpG island 3 location
Rl23mrp Biallelic Exon 1 (−100 to +300) None None
H19 Maternal Upstream (−600 to −250) Intron 1 (+800 to +1300) Downstream (+6500 to +6700)
Igf2 Paternal Upstream (−1960 to −2760) Exon 1 (+500 to +1800) Intron 2 (+2400 to +2800)
Ins Biallelic None None None
Th Biallelic None None None
Mash2 Maternal Exon 1 (−500 to +900) Downstream (+1100 to +1600) None
Tssc6 Biallelic Intron 7 (+10500 to +10900) None None
Tapa1 Unknown Upstream (−1500 to −600) None None
Tssc4 Biallelic Exon 1,2 (−300 to +400) None None
Trpc5l Biallelic None None None
Kvlqt1 Maternal Exon 1 (−400 to +300) Intron 10 Intron 15
Lit1 Paternal Upstream (−1600 to −1200) None None
p57KIP2 Maternal Upstream (−2300 to −2700) Exons 1,2,3 None
Msuit Maternal Upstream (−1000 to −3500) Downstream (+2000 to +2800) None
Tssc5 Maternal Upstream (−1100 to −900) Intron 6 None
Tssc3 Maternal Upstream (−1300 to −1100) Exon 1 (−500 to +300) None
Nap1l4 Biallelic None None None
  • Considered imprinted if imprinted in the predominantly expressing tissues at some stage of development.

  • Locations are calculated with respect to the start site of transcription.

  • More than 3 CpG islands are not listed.

This Article

  1. Genome Res. 10: 1697-1710

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