Classification of Transmembrane Protein Families in the Caenorhabditis elegans Genome and Identification of Human Orthologs

Table 3.

Causes of Incorrect Orthology Assignments by Two-Way BLAST

Reason 2 segments Gap penalties Constant molecular clock No rooting with outgroup Total
False negatives 2 4 0 0  6
False positives 3 4 5 5 17

  • See text for details.

This Article

  1. Published in Advance November 8, 2000, doi: 10.1101/gr.GR-1491R Genome Res. 10: 1679-1689

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