Classification of Transmembrane Protein Families in the Caenorhabditis elegans Genome and Identification of Human Orthologs

Non-human orthologs are shown only in groups where the corresponding human gene is missing. The names starting with letters AAC, AAD, AAF, BAA, CAA or CAB are coding sequences from EMBL database, not indexed in TREMBL. They can be retrieved by searching “proteinID” field in “EMBL_features” database. The C. elegans orthologs for which worm EST sequences are known are shown in bold. The description column shows brief information from the SWISSPROT or TREMBL description field (uppercase) and from other sources (lowercase). The last column shows the reliability index (average bootstrap value) for orthologous pairs. Families are organized into groups by their general biochemical function. Functional categories not shown here include Enzymes, Transporters and ion channels, Miscellaneous receptors and adhesion molecules, Exact biochemical function unknown, and Matches to mammalian or human genomic sequences. The complete table is available as supplementary information at http://www.genome.org.