Figure 3.
Is the collection of Homo sapiens genomic sequence biased? We computed the probability that cDNAs of a particular GC content aligned to genomic seqence, given that only 369 Mb of nonredundant finished genomic sequence were available. The solid line (on an arbitrary scale) indicates the initial collection of cDNAs. The obvious bias toward GC-rich cDNAs is important because these are known to correspond to smaller genes (Bernardi 2000). Dark shading shows strong hits; light shading shows weak hits.
