Is “Junk” DNA Mostly Intron DNA?

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

Is the collection of Homo sapiens cDNA sequence biased? We aligned the 1,856,102 ESTs in GenBank to our cDNA sequences and plotted the number of aligned ESTs as a function of the genomic length. Multiple reads from the same clone are counted only once. There is no obvious bias, indicating that cDNAs for genes of every genomic length are equally easy to isolate.

This Article

  1. Genome Res. 10: 1672-1678

Preprint Server