Spatially Restricted Hypopigmentation Associated with an Ednrbs -Modifying Locus on Mouse Chromosome 10

Table 4.

Test Crosses of C3H and Mayer alleles of k10 Using theMgfSl  Mutation

Hypopigmentation Mgf Sl /Mgf C3H Mgf C3H /Mgf C3H Mgf Sl /Mgf Mayer Mgf C3H /Mgf Mayer
Head spot F1 100% (8/8) 0% (0/6) 0% (0/2) 0% (0/2)
BC1 100% (14/14) 0% (0/11) 0% (0/11) 0% (0/6)
Dorsal spot F1 0% (0/8) 0% (0/6) 50% (1/2) 0% (0/2)
BC1 0% (0/14) 0% (0/11) 73% (8/11) 0% (0/6)
  • Ranged from several white hairs to large spot.

  • From matings of C3HeBFeJ/LeMgfSl/MgfC3H; × C3HeBFeJ/Le MgfC3H; Ednrbs (forMgfSl/MgfC3H andMgfC3H/MgfC3H mice) and C3HeBFJ/Le MgfSl/MgfC3H;× Mayer MgfMayer; Ednrbs (forMgfSl/MgfMayer andMgfC3H/MgfMayer mice). All mice are Ednrbs/Ednrb+.

  • From matings of C3HeBFej/LeMgfSl/MgfC3H; × (C3HeBFeJ/Le MgfC3H; Ednrbs × Mayer MgfMayer; Ednrbs ) F1. All mice are Ednrbs/Ednrb+.

  • Fisher's exact test p < 0.001.

This Article

  1. Genome Res. 10: 17-29

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