Spatially Restricted Hypopigmentation Associated with an Ednrbs -Modifying Locus on Mouse Chromosome 10

Table 1.

Distribution of Phenotypes in Parental Strains and Crosses

Strain or cross No. Vental percent white Dorsal percent white Total percent white Head percent white
C3HEdnrbs/Ednrbs 17 25.77 ± 5.61 2.89 ± 1.21 14.96 ± 3.25 2.88 ± 1.32
MayerEdnrbs/Ednrbs 28 67.73 ± 6.78 38.17 ± 10.35 53.50 ± 6.24 .198 ± .352
(MayerEdnrbs/Ednrbs × C3HEdnrbs/Ednrbs ) F1 12 31.26 ± 7.88 2.99 ± 3.01 17.30 ± 5.85 1.00 ± 1.651
(MayerEdnrbs/Ednrbs × C3HEdnrbs/Ednrbs ) F1  × MayerEdnrbs/Ednrbs 291 48.96 ± 12.24 15.22 ± 13.37 32.09 ± 11.57 not measured
(Mayer Ednrbs/Ednrbs × C3HEdnrbs/Ednrbs ) F1  × MayerEdnrbs/Ednrbs  d 91 55.70 ± 10.40 24.0 ± 15.60 39.80 ± 11.80 1.40 ± 1.50
(MayerEdnrbs/Ednrbs × C3HEdnrbs/Ednrbs ) F1  × (Mayer Ednrbs/Ednrbs × C3HEdnrbs/Ednrbs ) F1 113 39.66 ± 13.54 9.940 ± 11.87 24.89 ± 11.78 1.77 ± 2.00
  • Number of animals analyzed.

  • Mean percentage of hypopigmentation ±1 s.d

  • Initial backcross described in Pavan et al. (1995)

  • Additional backcross used to confirm linkage.

This Article

  1. Genome Res. 10: 17-29

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