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Method:Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale
in the hierarchical folding of chromosomes
Yinxiu Zhan,
Luca Mariani,
Iros Barozzi,
Edda G Schulz,
Nils Bluthgen,
Michael Stadler,
Guido Tiana,
and Luca Giorgetti
Genome Res. January 5, 2017 gr.212803.116; Published in Advance January 5, 2017, doi:10.1101/gr.212803.116