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Method:Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale
in the hierarchical folding of chromosomes
Yinxiu Zhan,
Luca Mariani,
Iros Barozzi,
Edda G. Schulz,
Nils Blüthgen,
Michael Stadler,
Guido Tiana,
and Luca Giorgetti
Genome Res. March 2017 27: 479-490; Published in Advance January 5, 2017, doi:10.1101/gr.212803.116