Effect of Expression Breadth on Significance of Local Similarity in KA (Duplicate Genes Excluded)
Human—mouse | Mouse—rat | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Breadth measurea | ρ | Pallb | Pgroupc | N | ρ | Pallb | Pgroupc | N | ||||||
| EST | 0.047 | 0.0072 | 0.016 | 3115 | 0.023 | 0.10 | 0.069 | 3029 | ||||||
| SAGE | 0.041 | 0.032 | 0.044 | 2572 | 0.041 | 0.024 | 0.020 | 2740 | ||||||
| Microarray | -0.037 | 0.90 | 0.92 | 1209 | 0.038 | 0.071 | 0.049 | 1559 | ||||||
a Breadth of expression was averaged over experiments in human and mouse for the human—mouse comparison, and was obtained from mouse only in the mouse—rat comparison.
b Pall is the number of equal or greater ρ in datasets obtained by randomly permuting all genes.
c Pgroup is the number of equal or greater ρ in datasets obtained by randomly permuting genes within classes of similar expression breadth.