Table 5.

Association Between Segmental Duplications and Gene Expression Differences

Expressed genes
Differently expressed genes
Higher in humans
Higher in chimpanzees
Duplicationsa
Detected
%
Detected
%
p-valueb
Detected
%
p-value
Detected
%
p-value
90%-95% 663 3.6 7.4 3.7 0.049 51 4.1 0.043 23 3.1 0.064
95%-98% 448 2.4 59 3.0 0.024 37 3.0 0.039 22 2.9 0.063
98%-100% 483 2.6 120 6.0 <0.0001 103 8.2 <0.0001 17 2.3 0.083
All genes
18,340
100
1999
100
1250
100
747
100

a Grouped by the percent of sequence identity between the duplicated copies.

b p-values calculated using Fisher's Exact test.