Table 3.

Pairwise Distance Comparisons of Transcription Factorsa

Transcription Factor
Component of RNAP I, II or III
Crown Distanceb
Crown/Giardia Distance
Crown/Archaea Distancec
Archaea/Giardia Distance
TBP I II III 41 246 123 217
TFIIH P90 II 73 158
TFIIH P80 II 74 181
TFIIH Cdk7 II 92 110
TFIIA γ II 99
TFIIB II 113 151
TFIIH P44 II 120 256
TFIIH P52 II 126
TFIIH MAT1 II 159
TFIIH P34 II 176 289
BRF III 191 259 204 247
TFIIH Cyclin H II 199
TFIIF β II 210
TFIIA αβ II 222
TFIIE β II 232
TFIIE α II 244 298
TFIIH P62 II 265
TFIIIC 102 III 270
RRN3 I 287 481
TFIIIC 63 III 303
TFIIIA III 339
TFIIF α II 349
TFIIIB B90
III
385

a Distance is the estimated number of replacements per 100 amino acids. Proteins highlighted in bold have a giardial homolog. Factors are sorted from least to greatest Crown Distance.

b Inter-kingdom distances only; the animal—animal and fungus—fungus values are excluded

c Archaea are represented by Methanococcus jannaschii and Sulfolobus solfataricus