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Table 2.

Compilation of SR proteins identified in the analyzed genomes

Family	Human	Mouse	Rat	Chicken	Fugu	Zebrafish	Tetraodon	Ciona	Fly	Mosquito	C. elegans	Arabidopsis	S. pombe	Plasmodium	T. cruzi
9G8-SRp20	9G8	9G8	9G8	9G8a	9G8	9G8a	9G8	9G8a	9G8	9G8	RSP6	RS21
	SR20	SR20	SR20	9G8b	SR20a	9G8b	SR20	9G8b	RBP1	RBP1	RSPY	RS22
				SR20	SR20b	9G8c		SR20	RBP1L	RSF1		RS22A
						SR20a			RSF1			RS32^a
						SR20b						RS33^a
p54	p54	p54	p54	p54	p54a	p54	p54a	SR86a	p54	p54	p54
	SR86	SR86	SR86	SR86	p54b	SR86	p54b	SR86b
					SR86		p54c
RY1	RY1	RY1	RY1	RY1	RY1		RY1	RY1	RY1	RY1	RY1	RY1
SC35	SC35	SC35	SC35	SC35	SC35a	SC35a		SC35	SC35	SC35	SC35	SC28^a	SRP1^b
	SR46				SC35b	SC35b						SC30^a
												SC30A^a
												SC33^a
												SC35
SRm300	SR300	SR300	SR300		SR300	SR300	SR300	SR300	SR300	SR300	SRRM2	SR45		SF^b
SRp30c-ASF	ASF	ASF	ASF	ASF	ASFa	ASFa	ASF	ASFa	SF2	SF2	SF2	RS31A^a
	SR30C	SR30C	SR30C		ASFb	ASFb		ASFb				SR34
					SR30C	SR30C						SR34A
												SR34B
												SRp30
SRp40-55-75	SR40	SR40	SR40	SR40a	SR40a	SR40a	SR40a	SR40a	SR55	SR40	RSP1	RSp31^a	SRP2^b		SR1^b
	SR55	SR55	SR55	SR40b	SR40b	SR40b	SR40b	SR40b			RSP2	RSp40^a
	SR75	SR75	SR75	SR55	SR55	SR55a		SR40c			RSP5	RSP41^a
				SR75	SR75	SR55b		SR55
						SR75
Topol-B	T1B	T1B	T1B	T1B	T1Ba	T1Ba	T1Ba		T1B	T1B
					T1Bb	T1Bb	T1Bb
Tra2	Tra2A	Tra2A	Tra2A	Tra2A	Tra2B	Tra2A	Tra2B	Tra2	Tra2	Tra2a	Tra2
	Tra2B	Tra2B	Tra2B	Tra2B		Tra2B				Tra2b

Detailed identification of each gene is provided in Table S2. Small termination characters identify species/phylum specific duplications. None of the analyzed SR protein genes was found for Saccharomyces cerevisiae.

a Arabidopsis-specific SR proteins, technically considered orthologs of the human proteins in the same family (reciprocal BLAST hit) but exhibiting a considerably lower degree of identity with the human factor than their Arabidopsis paralogs

b SR proteins in unicellular eukaryotes can be considered common homologs of all the SR proteins in metazoans; here we include them in the same families of their technical human orthologs (reciprocal BLAST hit)