Frequency and class of gene/protein predictions (Ensembl, June 2004)
Gene family | Number | Function |
|---|---|---|
| tRNA | 280 | Transfer RNA, adaptor in translation |
| 5S rRNA | 12 | Ribosomal RNA, component of ribosome |
| 5.8S RNAa | ∼145 | Ribosomal RNA, component of ribosome |
| 18S rRNAa | ∼145 | Ribosomal RNA, component of ribosome |
| 28S rRNAa | ∼145 | Ribosomal RNA, component of ribosome |
| snRNP U1 | 18 | Major spliceosome |
| snRNP U2 | 6 | Major spliceosome |
| snRNP U4 | 4 | Major spliceosome |
| snRNP U5 | 9 | Major and minor spliceosomes |
| snRNP U6 | 15 | Major spliceosome |
| snRNP U4atac | 1 | Minor spliceosome |
| snRNP U6atac | 4 | Minor spliceosome |
| snRNP U11 | 1 | Minor spliceosome |
| snRNP U12 | 1 | Minor spliceosome |
| miRNA | 121 | Translation repression |
| snoRNA | 83 | Small nucleolar RNA, takes part in processing of rRNA |
| RNaseP | 1 | Ribozyme, processes tRNA |
| snRNP U7 | 1 | 3′-end processing of replication-dependent histone pre-mRNAs |
| SRP | 3 | RNA component of signal recognition particle |
| 7SK | 4 | Binds P-TEFb, which activates transcription by phosphorylating C-terminal domain of RNA Pol II. This process is negatively regulated by the 7SK RNP. |
| Y RNA | 2 | Component of the Ro RNP, in association with Ro60 and La, function of Ro RNP not known. |
| Telomerase RNA | 1 | Provides the template for telomeric DNA addition |
| BIC | 1 | Cooperates with c-myc in B lymphomagenesis and erythroleukemogenesis |
| Total RNA genes | 571 (1441 incl. rRNA genes) | |
| Total pseudogenes | 75 | |
| Total protein coding genes | 17,709 |
a Ribosomal DNA 40-kb repeat (18S, 5.8S, 28S); Muscarella et al. (1985)