Table 2.

The Allelic Gene Expression Ratios for Seven Genes in Multiple Tissues Measured by Quantitative PCR


Genes

SNP ID

Liver

Kidney

Heart

Othera

No. of fetuses
ZIM2b rs3143 >8.0 >8.0 >8.0 >8.0 3
SNRPNb rs705 >8.0 >8.0 >8.0 >8.0 3
TAP2b rs17034 3.22 ± 1.57 1.90 ± 0.88 4.67 ± 2.88 2.19 ± 0.89 7
ELAC2b rs2523 2.33 ± 0.87 2.55 ± 0.54 2.92 ± 0.73 2.86 ± 0.52 7
DKFZP727G051b rs1837 2.80 ± 1.05 2.32 ± 0.53 2.16 ± 0.41 2.05 ± 0.43 7
UGDH rs1450 1.53 ± 0.72 1.44 ± 0.29 1.39 ± 0.14 1.49 ± 0.35 3
C11orf23
rs1996
1.52 ± 0.27
1.38 ± 0.39
1.52 ± 0.29
1.22 ± 0.16
2

The values are the ratios (allele A/allele B) between the two alleles. The values were inverted if less than one (allele B/allele A, when allele B was preferentially expressed). The mean ± SD is provided for allelic gene expression in the various tissues

a Several different fetal tissues were used, including adrenal, limb, and lung

b Allelic difference in gene expression is significantly deviated from equal expression (95% confidence interval). The confidence interval was generated from heterozygous DNAs