Table 2.

Duplicate Genes With Low Divergence in Gene Expression

Protein 1
Protein 2
KA
KS
N expra
Rb
Function of protein 1
Function of protein 2
Duplicates in which both genes are expressed in the same tissues
    BAA06336 CAA85523 0.705 3.01 25 <0.8 eukaryotic initiation factor 4All nuclear RNA helicase (DEAD family)
    AAC50682 BAA13199 0.256 3.12 24 <0.8 cytoplasmic phosphoprotein similar to mouse dishevelled-3
    AAB53494 AAC95431 0.378 3.35 22 <0.8 tub homolog tubby-like protein 3
    AAA35720 BAA07703 0.548 3.41 25 <0.8 cysteine-rich protein ESP1/CRP2
    AAB28361 CAA64685 0.220 3.47 25 <0.8 actin depolymerizing factor cofilin
    AAB06274 AAC63143 0.563 3.51 24 <0.8 vascular endothelial growth factor B precursor vascular endothelial growth factor
    AAA36446 CAA40621 0.092 3.71 25 <0.8 phospholipase A2 HS1
    AAA51813 CAA80661 0.615 3.74 1 n/ac bcl2-α protein unknown function
    BAA26001 CAA54793 0.581 3.77 1 n/a CDC2δT CDK-activating kinase
    AAC95472 CAA27856 0.450 3.79 20 <0.8 connexin 31.1 gap junction protein
    BAA13327 CAA42060 0.306 3.80 24 <0.8 rhodanese unknown function
    AAA92734 AAC99402 0.728 3.83 25 <0.8 prosomal protein P30-33K proteasome subunit HSPC
    AAA58455 CAA34651 0.484 3.90 25 <0.8 amplaxin haematopoietic lineage cell protein
    AAA60190 CAA52882 0.670 3.91 25 <0.8 peripherin keratin 8
    AAA52620 CAA56071 0.628 3.91 25 <0.8 γ-tubulin β-tubulin
    AAA36501 CAA26528 0.716 4.04 2 n/a protein Z protein C precursor
    AAC62107 AAC62108 0.403 4.11 14 <0.8 UP50 UPH1
    AAA74425 CAA47732 0.288 4.17 1 n/a preprocarboxypeptidase A2 unknown function
    BAA76708 CAB46271 0.534 4.19 25 <0.8 RuvB-like DNA helicase TIP49b erythrocyte cytosolic protein
    AAA35563 AAA35568 0.504 4.24 25 0.82 aspartate aminotransferase aspartate aminotransferase precursor
    AAA70225 BAA08576 0.807 4.32 1 n/a coagulation factor XII precursor HGF activator-like protein
    AAA35705 AAB23769 0.161 4.33 1 n/a calcineurin A1 calcineurin A catalytic subunit
    BAA03095 CAA55908 0.094 4.34 25 <0.8 human rab GDI GDP-dissociation inhibitor
    AAC15920 BAA75899 0.438 4.39 25 <0.8 copine I N-copine
    AAA36025 AAA87704 0.748 4.40 25 <0.8 90-kD heat-shock protein TNF1 receptor-associated protein
    AAB97309 CAA88401 0.116 4.42 25 <0.8 polyadenylate binding protein polyadenylate binding protein II
    AAA51582 AAC17470 0.110 4.48 25 <0.8 α-actinin α-actinin
    CAA41149 CAA41176 0.456 4.60 25 <0.8 erythrocyte α-adducin β-adducin
    BAA05393 BAA07641 0.319 4.68 25 <0.8 homolog of female sterile homeotic mRNA female sterile homeotic (fsh) homolog RING3
    AAA64895 CAA61107 0.258 4.74 25 <0.8 plakoglobin β-catenin
    AAA80559 BAA25173 0.103 4.77 18 <0.8 transcription activator hSNF2H
    BAA07238 CAA50709 0.381 4.86 25 <0.8 proteasome subunit Z proteasome-like subunit MECL-1
    BAA24855 CAA12204 0.507 4.86 15 <0.8 unknown function ZNF198 protein
Gene pairs with R > 0.8
    AAA36338 AAA36458 0.291 3.74 >5 0.83 interferon-induced Mx protein p78 protein
    AAC96325 BAA11179 0.154 3.94 >5 0.86 ZIC2 protein Zic protein
    AAA20580 AAA58248 0.674 4.11 >5 0.87 Mu opiate receptor somatostatin receptor isoform 2
    AAA60316 AAB48394 0.644 4.07 >5 0.87 serotonin 1D receptor 5-hydroxytryptamine 7 receptor isoform d
    AAA52451
AAA52644
0.336
4.15
>5
0.91
p55-c-fgr protein
protein tyrosine kinase

a N expr is the number of tissues in which both genes of a pair are expressed

b R is the correlation coefficient between the expression levels of the two genes over the tissues studied

c n/a is not applicable because the number of tissues in which at least one of the duplicates is expressed was less than five