Table 2.

The Characteristics of the Missing Enzymes in Tryptophan Metabolism


EC number

Enzyme name

Inferred cDNA clone

Why the enzyme seemed to be missing
3.5.1.9 arylformamidase 9030621K19 Recently cloned, so not in GO yet
1.14.13.9 kynurenine 3-monooxygenase 4930567E01 Possible error in the assignment of GO terms
1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase 0610012J07 Enzyme name was registered, but EC number was not in GO
*4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase F530007C24 Recently cloned, so not in GO yet
*1.2.1.32 aminomuconate-semialdehyde dehydrogenase Not found
*1.5.1.-
2-aminomuconate reductase
Not found

[i] Enzymes with asterisk show no reference sequences in the public database. See details in the text