Table 2.

Fractions of Consistent Transcription Factor Target Genes in the Yeast Regulatory Network Classified by the Functional Class of the Target

MRM
TM
Number of regulators
Functional class
n
P < 0.01
P < 0.005
P < 0.001
n
P < 0.01
P < 0.005
P < 0.001
1
2
3
4
>4
Pheromone response 10 0.4 0.4 0.3 30 0.37 0.27 0.13 6 8 5 3 8
Detoxification 16 0.38 0.38 0.31 27 0.33 0.22 0.07 11 10 4 0 2
Nucleotide metabolism 21 0.33 0.24 0.19 25 0.28 0.2 0.2 3 16 3 3 0
DNA synthesis and replication 11 0.27 0.27 0.18 18 0.17 0.06 0 8 6 2 1 1
Amino acid metabolism 35 0.26 0.2 0.11 61 0.39 0.33 0.18 23 14 16 5 3
Carbohydrate metabolism 50 0.26 0.18 0.12 83 0.2 0.13 0.06 26 22 20 3 12
Mitotic cell cycle and cell cycle control 27 0.22 0.22 0.19 43 0.14 0.14 0.02 18 14 5 1 5
Nitrogen and sulfur metabolism 14 0.14 0.14 0.07 28 0.39 0.39 0.32 5 9 6 6 2
Cellular import 18 0.11 0.11 0.06 21 0.29 0.29 0.14 5 9 5 2 0
Stress response 18 0.11 0.11 0.11 29 0.1 0.07 0.07 12 8 5 1 3
Meiosis 20 0.1 0.1 0.1 26 0.04 0.04 0 12 7 2 1 4
mRNA synthesis 34 0.06 0.06 0.03 64 0.16 0.11 0.06 30 18 6 1 9
Lipid, fatty-acid and isoprenoid metabolism 30 0.03 0.03 0.03 39 0.13 0.13 0.05 20 8 5 4 2
DNA recombination and DNA repair 11 0 0 0 19 0.05 0.05 0 10 4 3 1 1
Sporulation and germination
8
0
0
0
17
0.12
0.06
0
5
6
2
2
2

[i] See caption for Table 1 for details. The functional classes were obtained from the MIPS database (Mewes et al. 2002).