Amino Acid Usage and Expression Level (SAGE), Multiple Regression Analysis
Amino acid | One letter code | Pearson correlation with expression (p < 0.0001) | Effect of expression when controlling for GC3 content and gene length (p < 0.0001) |
|---|---|---|---|
| Alanine | A | 0.100 | β = 0.336 |
| Arginine | R | NS | — |
| Aspargine | N | NS | — |
| Aspartic acid | D | 0.100 | β = 0.562 |
| Cysteine | C | −0.077 | β = −0.458 |
| Glutamine | Q | −0.071 | β = −0.256 |
| Glutamic acid | E | 0.055 | β 0.561 |
| Glycine | G | 0.084 | β 0.418 |
| Histidine | H | −0.118 | β = −0.349 |
| Isoleucine | I | NS | — |
| Leucine | L | −0.105 | β = −0.888 |
| Lysine | K | 0.126 | β = 1.049 |
| Methionine | M | 0.071 | β = −0.142 |
| Phenylalanine | F | −0.032 | β = −0.155 |
| Proline | P | −0.045 | β = −0.401 |
| Serine | S | −0.145 | β = 0.785 |
| Threonine | T | 0.045 | β = −0.086 |
| Tryptophan | W | −0.071 | β = −0.211 |
| Tyrosine | Y | NS | — |
| Valine | V | 0.055 | β = 0.227 |
[i] Threshold of significance is defined after Bonferroni correction.