Table 1.

Average properties (with standard errors) of the 50 data sets in the simulation study underlying Tables 2, 3, 4, 5, 6


FST/struct

FST (%)

|#cont – #case|

λ
(1) No structure 1.2 (0.03)
(2) Low/eq 3.5 (0.1) 24 (2) 1.2 (0.04)
(3) High/eq 8.3 (0.1) 43 (4) 1.9 (0.19)
(4) Low/un 3.5 (0.1) 19 (2) 1.2 (0.05)
(5) High/un
8.4 (0.1)
20 (2)
1.4 (0.06)

[i] The first column gives a short label for each of the five demographic scenarios described in the text. Columns 2–4 give the average maximum-likelihood estimate of FST; the average absolute difference between the numbers of cases and of controls drawn from one population; and the average estimate of the λ parameter of the genomic control method.