An example of phylogenetic correlation between the transcription factor trpR and its regulon
Species | TF | Regulon conservation |
|---|---|---|
| E. coli | 1 | 1.0000 |
| H. influenzae | 1 | 0.3953 |
| P. multocida | 1 | 0.5237 |
| P. aeruginosa | 0 | −0.0399 |
| P. putida | 0 | 0.0297 |
| P. syringae | 0 | 0.0507 |
| S. oneidensis | 0 | 0.0866 |
| S. typhi | 1 | 0.9721 |
| V. cholerae | 1 | 0.9664 |
| V. parahaemolyticus | 1 | 0.3588 |
| V. vulnificus | 1 | 0.8106 |
| X. campestris | 0 | −0.0495 |
| Y. pestis | 1 | 0.2105 |
[i] “1” indicates the existence of a trpR ortholog in the given species, “0” otherwise. The degree of regulon conservation is calculated using E. coli as the reference species (see Methods for calculation). The phylogenetic correlation is PCtrpR = 0.8016.