Compartmentalization of duplicate gene families in S. cerevisiae metabolism
Duplicate families | ORF | Localizationa | Growth phenotypeb | Essential reactionc | Duplication eventd |
|---|---|---|---|---|---|
| AAT1 | YKL106W | mit | +/+/+/+/+ | -/+/+/+/+ | |
| AAT2 | YLR027C | cyt | +/+/+/+/+ | ||
| ACC1 | YNR016C | cyt | -e | +/+/+/+/+ | Genome duplication |
| HFA1 (ACC2) | YMR207C | mit | +/+/+/+/+ | Genome duplication | |
| ADH1 | YOL086C | cyt | +/+/+/+/+ | -/-/-/-/+ | |
| ADH2 | YMR303C | cyt | +/+/+/+/+ | ||
| ADH3 | YMR083W | mit | +/+/+/+/+ | ||
| ADH4 | YGL256W | mit | +/+/+/+/+ | Genome duplication | |
| ADH5 | YBR145W | cyt | +/+/+/+/+ | Genome duplication | |
| ADK1 | YDR226W | cyt | +/+/+/+/- | +/+/+/+/+ | |
| ADK2 | YER170W | mit | +/+/+/+/+ | ||
| ALD4 | YOR374W | mit | +/+/+/+/+ | -/-/-/-/+ | |
| ALD5 | YER073W | mit | +/+/+/+/+ | ||
| ALD6 | YPL061W | cyt | +/+/+/+/+ | ||
| ALT1 | YLR089C | mit | +/+/+/+/+ | -/-/-/-/- | Genome duplication |
| ALT2 | YDR111C | cyt | +/+/+/+/+ | Genome duplication | |
| BAT1 | YHR208W | mit | + | +/+/+/+/+ | Genome duplication |
| BAT2 | YJR148W | cyt | +/+/+/+/+ | Genome duplication | |
| CIT1 | YNR001C | mit | +/+/+/+/+ | -/+/+/+/+ | Genome duplication |
| CIT2 | YCR005C | cyt | +/+/+/+/+ | Genome duplication | |
| CIT3 | YPR001W | mit | +/+/+/+/+ | ||
| DLD1 | YDL174C | mit | +/+/+/+/+ | -/-/-/-/- | |
| DLD2 | YDL178W | mit | +/+/+/+/+ | ||
| DLD3 | YEL071W | cyt | + | ||
| GLO2 | YDR272W | cyt | +/+/+/+/+ | -/-/-/-/- | |
| GLO4 | YOR040W | mit | +/+/+/+/+ | ||
| GPD1 | YDL022W | cyt | +/+/+/+/+ | -/-/-/-/- | Genome duplication |
| GPD2 | YOL059W | cyt/mit | +/+/+/+/+ | Genome duplication | |
| IDP1 | YDL066W | mit | +/+/+/+/+ | -/-/-/-/- | |
| IDP2 | YLR174W | cyt | +/+/+/+/+ | Genome duplication | |
| IDP3 | YNL009W | cyt | +/+/+/+/+ | Genome duplication | |
| LEU4 | YNL104 | cyt | +/+/+/+/+ | -/-/-/-/- | Genome duplication |
| LEU9 | YOR108W | mit | +/+/+/+/+ | Genome duplication | |
| MDH1 | YKL085W | mit | +/+/+/+/+ | -/-/-/-/+ | |
| MDH2 | YDL078C | cyt | +/+/+/+/- | ||
| MDH3 | YOL126C | cyt | +/+/+/+/+ | ||
| IPP1 (PPA1) | YBR011C | cyt | - | +/+/+/+/+ | |
| PPA2 | YMR267W | mit | +/+/-/-/- | ||
| PSD1 | YNL169C | cyt | +/+/+/+/+ | -/-/-/-/- | |
| PSD2 | YGR170W | mit | +/+/+/+/+ | ||
| SHM1 | YBR263W | mit | +/+/+/+/+ | -/-/-/-/- | |
| SHM2 | YLR058C | cyt | +/+/+/+/+ | ||
| TRR1 | YDR353W | cyt | + | -/-/-/-/- | Genome duplication |
| TRR2 | YHR106W | mit | +/+/+/+/+ | Genome duplication |
a According to Huh et al. (2003). (cyt) cytosol; (mit) mitochondria
b Experimental phenotype on YPD, glucose, galactose, glycerol, or ethanol-containing media
c In silico phenotype predictions on YPD, glucose, galactose, glycerol, or ethanol as the carbon source
d According to Dietrich et al. (2004)
e According to SGD (http://www.yeastgenome.org/)