Table 1.

Pathways Analyzed and Percentage Showing Significant Clustering in Unmerged and Merged Data Sets

Organism
# Pathways analyzed
# Genes
% Significant unmerged data
% Significant merged data
% in random data
H. sapiens 98 975 78% 65% 11%
C. elegans 86 516 74% 58% 11%
D. melanogaster 85 484 50% 30% 12%
A. thaliana 79 318 60% 43% 11%
S. cerevisiae
89
682
35%
20%
10%

[i] The percent significant refers to pathways in which the score is more than 3* (3rd quartile – median) + median. The same analysis was carried out on randomized pathways where genes were picked randomly from all genes, using the merged data