Table 1.

Summary of In Silico Analysis of the S/MAR Domain of 20p12 Neocentromere




S/MAR domain

Non-S/MAR domain

p-value
AT content 60.9% 60.7% 0.646
Poly(A) tracts 1802 1790 0.840
MarWiz 3.7 3.5 0.511
Smartest 10.4 9.1 0.630
ChrClass
17.7
16.9
0.777

[i] To facilitate statistical analysis, AT content was calculated for the whole region, whereas the frequency of poly(A) tracts and S/MAR predictions, using MarWiz, Smartest, and ChrClass were calculated per 100 kb. P-values from t-tests comparing the S/MAR-enhanced and non-S/MAR-enhanced domains are given.