Table 1.

General Features of S. pyogenes Strains SSI-1, SF370, MGAS315, and MGAS8232



Strains
Features
SSI-1 (M3)
SF370a(M1)
MGAS315b(M3)
MGAS8232c(M18)
Length of sequence (bp) 1,894,275 1,852,441 1,900,521 1,895,017
G+C content 37.93% 38.51% 38.6% 38.5%
Open reading frames
Percentage coding 85.94% 83.77% 85.76% 84.94%
Protein coding region 1861 1696 1865 1845
Average gene length (bp) 853 915 874 872
SNPs (per gene)d
Average number of SNPs — 11.53 0.05 12.61
Silent SNPs (sSNPs) — 6.40 0.02 7.26
Coding SNPs (cSNPs) — 5.13 0.03 5.35
RNA
Ribosomal RNA 5 6 6 6
Transfer RNA 57 60 60 60
tmRNA 1 1 1 2
Transposon or IS 21 17 22 25
Phage-related
Pro-phage 6 4 6 5
Remnant
4
4
3
3

a,b,c The genomic sequences of other S. pyogenes strains (SF370:AE004092, MGAS8232: AR009949 and MGAS315: AE014074) were obtained through the Web site of the NCBI, http://www.ncbi.nlm.nih.gov.

d SNPs in orthologous genes of strain SSI-1 were compared with those of strains SF370, MGAS315, and MGAS8232.