Table 1.

Results of HOPS and RIO for the Test Set of Putative Orthologs for H. sapiens and D. melanogaster

H. sapiens
D. melanogaster
Domain
HOPS (%)
RIO (%)
143E_HUMAN 143E_DROME 14-3-3 100 98
ADHX_HUMAN ADHX_DROME adh_zinc 16.5 0
APE1_HUMAN RRP1_DROME Exo_endo_phos 100 85
ARF1_HUMAN ARF1_DROME arf 89.5 92
ARI1_HUMAN ARI1_DROME IBR 100 96
ARL1_HUMAN ARL1_DROME arf 100 100
ATPG_HUMAN ATPG_DROME ATP-synt 100 100
ATPO_HUMAN ATPO_DROME OSCP 100 63
CAPB_HUMAN CAPB_DROME F_actin_cap_B 100 95
CG1C_HUMAN CG1C_DROME Cyclin 100 80
CLAT_HUMAN CLAT_DROME Carn_acyltransf 94 89
COXA_HUMAN COXA_DROME COX5A 99 78
DYNA_HUMAN DYNA_DROME CAP_GLY 50.5 29
ERH_HUMAN ER_DROME ER 100 98
FAC2_HUMAN FAC2_DROME Abi 87 62
H2AZ_HUMAN H2AV_DROME Histone 76 21
H4_HUMAN H4_DROME Histone 62 1
IF2A_HUMAN IF2A_DROME S1 78 62
KC2B_HUMAN KC2B_DROME CK_II_beta 18.5 36
MCM2_HUMAN MCM2_DROME MCM 100 97
MCM4_HUMAN MCM4_DROME MCM 100 100
PP1B_HUMAN PP1B_DROME Metallophos 76 43
PRS8_HUMAN PRS8_DROME AAA 84.5 —
PSA2_HUMAN PSA2_DROME Proteasome 99.5 98
PSA3_HUMAN PSA3_DROME Proteasome 74.5 13
PSA4_HUMAN PSA4_DROME Proteasome 100 100
PSA5_HUMAN PSA5_DROME Proteasome 79 95
PSA6_HUMAN PSA6_DROME Proteasome 77 44
PSB1_HUMAN PSB1_DROME Proteasome 50.5 37
PSB3_HUMAN PSB3_DROME Proteasome 72.5 22
PURA_HUMAN PURA_DROME Adenylsucc_synt 100 100
RA51_HUMAN RA51_DROME HHH 0 0
RBJK_HUMAN RBJK_DROME TIG 97 48
RLA1_HUMAN RLA1_DROME 60s_ribosomal 35 12
RLA2_HUMAN RLA2_DROME 60s_ribosomal 45.5 21
RPB2_HUMAN RPB2_DROME RNA_pol_B 100 96
RPB6_HUMAN RPB6_DROME RNA_pol_Rpb6 90 62
RS18_HUMAN RS18_DROME Ribosomal_S13 24 3
RTC1_HUMAN RTC1_DROME RTC 100 6
SSB_HUMAN SSB_DROME SSB 97.5 92
T2DA_HUMAN T2DA_DROME TFIID_A 82.5 87
T2FB_HUMAN T2FB_DROME TFIIF_beta 100 98
TCPA_HUMAN TCPA_DROME cpn60_TCP1 99.5 60
TCPG_HUMAN TCPG_DROME cpn60_TCP1 97 57
UBCI_HUMAN O62622 UQ_con 100 96
VATF_HUMAN VAF1_DROME ATP-synt_F 97 54
XPA_HUMAN
XPA_DROME
XPA
100
67

[i] A “—” indicates no results reported.