Results From Multiple-Regression Analyses of Level of Gene Expression and Length With Gene Parameters When Including GC3 Content
Dependent variable | Database | Pearson correlation with level of expression (p < 0.0001) | Effect of expression when controlling for regional effects (p < 0.0001) a |
|---|---|---|---|
| Protein length b | SAGE | R = 0.182 | β = −0.175 |
| Chip Array | R = 0.194 | β = −0.200 | |
| Intron length b | SAGE | R = 0.181 | β = −0.403 |
| Chip Array | R = 0.198 | β = −0.369 | |
| Codon bias (MCB) b | SAGE | R = 0.122 | β = 0.019 |
| Chip Array | R = 0.180 | β = 0.032 | |
| AA complexity b | SAGE | R = 0.062 | β = −0.006 |
| Chip Array | R = 0.045 | NS |
a Regional effects are gene density (average intergenic distance of two adjacent genes), base composition (intergenic base composition of 5000 bp at either side of gene), and recombination rate (average of recombination rate of nearest markers weighted by distance).
b Variables log transformed for analysis.