Table 7.

N. crassa Genes with Homologs in NF but Not HMEST[i]

Discontig Identification NF E-value[ii] EUTH E-value[iii]
II. Cell signaling/cell communication[iv]
  226Tap42p protein phosphatase subunit10−6  10−4  
IV. Cell/organism defense
  359low temperature and salt induced protein[v] 3 × 10−10 [vi]
 1069nitrilase[v] 9 × 10−11
V. Metabolism
   10thiamine-repressed protein (NMT1)10−23
  192thiamine biosynthetic enzyme9 × 10−37
  197amino acid permease (AAP2)10−6 
  266fructose 1,6-bisphosphate aldolase4 × 10−18
  287laccase (LAC1)[v] 2 × 10−7
  367methionine synthase (Met6p)10−41
  368nitrite reductase4 × 10−22
  445putative hydrolase[v] 2 × 10−7 0.02 
  466formate dehydrogenase5 × 10−11
  525peptide transporter (Ptr2p)2 × 10−11 5 × 10−5
  611phosphatidylserine synthase2 × 10−8 0.014
  637sulfite reductase5 × 10−10
  815isocitrate lyase (ACU-3)[v] 2 × 10−19
  880α-amylase10−5 
  935pyruvate-formate lyase activating enzyme8 × 10−10
  957Ca2+/H+ exchanger (Vcx1p)10−22
  962Putative oxidoreductase2 × 10−12
  980Δ24-sterol C-methyltransferase (Erg6p)[v] 2 × 10−21
 1011pyruvate decarboxylase2 × 10−19
 1058NADP-dependent glutamate dehydrogenase (AM)2 × 10−12
 1105cystathionine beta-synthase (Cys4p)4 × 10−6
VI. Protein synthesis
   82subtilisin-like serine proteinase7 × 10−13
Unclassified
  340ethylene-forming enzyme2 × 10−7
  467hypothetical protein, Streptomyces coelicolor 4 × 10−7
  667flavohemoglobin (Yhb1p)5 × 10−10
 1053carbonic anhydrase[v] 5 × 10−22
 1175homolog of Dem gene product from plants5 × 10−7 0.057
 1179hypothetical protein, Synechocystissp.2 × 10−31

[i] All sequences have no hit in the human/mouse EST data set (no E-value < 0.1).

[ii] E-value of best BLAST hit in nonfungal data set.

[iii] E-value of best BLAST hit in eutherian data set.

[iv] Functional categories are as described in Nelson et al. (1997), based on a modification of the system described by White and Kerlavage (1996).

[v] This discontig has a possible hit (E-value < 0.1) in C. elegans.

[vi] No eutherian database sequence received anE-value < 0.1.