Instances of Non-Orthologous Displacements
| No. | Pathway | EC number | Gene name(s) in E. coli | Gene name(s) in S. cerevisiae |
| 1 | Glycolysis/Gluconeogenesis | 2.7.1.2 | glk | glk1 |
| 2 | Glyoxylate and dicarboxylate metabolism | 1.2.1.2 | fdoI, fdoH, fdoG, fdnI, fdnH, fdnG, fdhf | YPL275W, YPL276W |
| 3 | Sulfur metabolism | 2.7.7.4 | cysN, cysD | met3 |
| 4 | Purine metabolism | 4.6.1.1 | cyaA | cyr1/cdc35/hsr1/sra4 |
| 5 | Arginine and proline metabolism | 4.1.1.17 | speF/speC | spe1 |
| 6 | Glycine, serine and threonine metabolism | 4.2.1.13 | sdaA, sdaB, sdhY | sdl1/cha1 |
| 7 | Glycine, serine and threonine metabolism | 3.1.3.3 | serB | ser2 |
| 8 | Aminosugars metabolism | 2.7.7.23 | glmU | qril1 |
| 9 | Glycerolipid metabolism | 3.1.4.46 | glpQ, ugpQ | YPL206C |
| 10 | Phospholipid degradation | 3.1.1.5 | tesA | plb1, plb3, lag2 |
| 11 | Porphyrin and chlorophyll metabolism | 1.3.3.4 | hemG | hem14 |
| 12 | Riboflavin metabolism | 2.7.7.2 | ribF | fad1 |
| 13 | Galactose metabolism | 2.7.7.9 | galU, galF | YHL012W, ugp1 |