Thyroid Hormone–Induced Up-Regulation of mRNA Expression for Genes Involved in Metabolism
| UniGene no. | Encoded protein | Pathway | Fold |
| Hs.77837 | UDP-glucose pyrophosphorylase 2 | Glycogen synthesis | 3.02 |
| Hs.1691 | Glycogen branching enzyme | Glycogen synthesis | 2.82 |
| Hs.169428 | Cytochrome c[ii] | Respiratory chain (complex IV) | 2.68 |
| Hs.2043 | Adenine nucleotide translocase 1 | Mitochondrial carrier | 2.66 |
| Hs.33084 | Fructose transporter GLUT 5[ii] | Glucose metabolism | 2.66 |
| Hs.78713 | Adenine nucleotide translocase 2[ii] | Mitochondrial carrier | 2.58 |
| Hs.74635 | Dihydrolipoamide dehydrogenase (pyruvate dehydrogenase complex E3) | Citric acid cycle | 2.58 |
| Hs.80595 | NADH dehydrogenase (ubiquinone) Fe-S protein 5 | Respiratory chain (complex I) | 2.54 |
| Hs.8364 | Pyruvate dehydrogenase kinase, isoenzyme 4[ii] | Citric acid cycle | 2.52 |
| Hs.19236 | NADH dehydrogenase (ubiquinone) 1 β subcomplex, 5 | Respiratory chain (complex I) | 2.50 |
| Hs.131255 | Ubiquinol–cytochrome c reductase binding protein | Respiratory chain (complex III) | 2.46 |
| Hs.155433 | ATP synthase, F1 complex, γ 1 | Respiratory chain (complex V) | 2.35 |
| Hs.101337 | Uncoupling protein 3[ii] | Mitochondrial carrier | 2.30 |
| Hs.81634 | ATP synthase, F0 complex, subunit b, isoform 1 | Respiratory chain (complex V) | 2.26 |
| Hs.109646 | NADH dehydrogenase (ubiquinone) 1 β subcomplex, 6 | Respiratory chain (complex I) | 2.23 |
| Hs.61255 | Fructose-1,6-bisphosphatase 2[ii] | Neoglucogenesis | 2.13 |
| Hs.1023 | Pyruvate decarboxylase (pyruvate dehydrogenase complex E1-α) | Citric acid cycle | 2.10 |
| Hs.429 | ATP synthase, F0 complex, subunit c, isoform 3 | Respiratory chain (complex V) | 2.09 |
| Hs.79876 | Steroid sulfatase, arylsulfatase C, isozyme S[ii] | Steroid hormone synthesis | 2.02 |
| Hs.73851 | ATP synthase, F0 complex, subunit F6 | Respiratory chain (complex V) | 2.02 |
| Hs.78060 | Phosphorylase kinase, β | Glycogenolysis | 2.00 |
| Hs.268012 | Long-chain fatty acid–coenzyme A ligase 3 | Lipid β oxidation | 1.99 |
| Hs.7043 | Succinate-CoA ligase, GDP-forming, α subunit | Citric acid cycle | 1.99 |
| Hs.74823 | NADH dehydrogenase (ubiquinone) 1 α subcomplex, 1 | Respiratory chain (complex I) | 1.96 |
| Hs.3462 | Cytochrome c oxidase subunit VIIc | Respiratory chain (complex IV) | 1.90 |
| Hs.76688 | Carboxylesterase 1 | Cholesterol metabolism | 1.86 |
| Hs.183435 | NADH dehydrogenase (ubiquinone) 1 β subcomplex, 1 | Respiratory chain (complex I) | 1.82 |
| Hs.74649 | Cytochrome c oxidase subunit VIc[ii] | Respiratory chain (complex IV) | 1.74 |
| Hs.77508 | Glutamate dehydrogenase 1[ii] | Citric acid cycle | 1.72 |
| Hs.177584 | 3-oxoacid CoA transferase | Citric acid cycle | 1.64 |
[i] The fold increase represents the mean of the five comparisons.
[ii] Proteins that have been shown to be positively regulated by thyroid hormones in rodents.