Table 3.

Extracellular Proteome Changes in the Absence of SPase II

Proteins ΔlspA
Metabolism of carbohydrates
AmyE−−
Csn
Metabolism of proteins
Epr
WprARR +
Metabolism of lipids
LipARR
Metabolism of phosphate
GlpQpst
Metabolism of the cell wall
LytDW
Transport/binding proteins
MntAlipo +
YxeBlipo +
Detoxification
PenP
Phage-related functions
XepA
XkdK
XkdM
XlyAW
Similar to unknown proteins
YncM
YolA−−
YrpD
YwoF
YxaK
YxkC

[i] +, Proteins present at elevated levels on the extracellular proteome of the ΔlspA strain. −, Proteins present at reduced levels. −−, Proteins that are no longer detected on the extracellular proteome of the ΔlspA strain. pst, Proteins that are induced upon phosphate starvation. RR, Proteins with a twin-arginine motif in the signal peptide.lipo, Lipoproteins. W, Extracellular proteins containing wall-binding repeats in the mature part of the proteins.