Table 3.

Extracellular Proteome Changes in the Absence of SPase II

Proteins ΔlspA
Metabolism of carbohydrates
AmyE−−
Csn−
Metabolism of proteins
Epr−
WprARR +
Metabolism of lipids
LipARR −
Metabolism of phosphate
GlpQpst −
Metabolism of the cell wall
LytDW −
Transport/binding proteins
MntAlipo +
YxeBlipo +
Detoxification
PenP−
Phage-related functions
XepA−
XkdK−
XkdM−
XlyAW −
Similar to unknown proteins
YncM−
YolA−−
YrpD−
YwoF−
YxaK −
YxkC−

[i] +, Proteins present at elevated levels on the extracellular proteome of the ΔlspA strain. −, Proteins present at reduced levels. −−, Proteins that are no longer detected on the extracellular proteome of the ΔlspA strain. pst, Proteins that are induced upon phosphate starvation. RR, Proteins with a twin-arginine motif in the signal peptide.lipo, Lipoproteins. W, Extracellular proteins containing wall-binding repeats in the mature part of the proteins.