Table 5.

Procedures in Four-Cycle Genotyping

First cycle1.  Genotyping for all DNA samples
2.  Importing genotype data intoGenoDB
3.  Detecting unresolved genotype data (including both missing data and genotype errors) byGenoDB
Second cycle1.  Re-genotyping for those unsolved genotype data in the first cycle
2.  Importing genotype data intoGenoDB
3.  Detecting unresolved genotype data by GenoDB
4.  Detecting inconsistent genotype data by performing Medelian PedCheck
Third cycle1.  Re-genotyping for those unsolved and inconsistent genotype data in the second cycle
2.  Repeating steps 2, 3, and 4 of the second cycle
Fourth cycle1.  Repeating Steps 1, 2, 3, and 4 of the third cycle
2.  Unresolved genotype data are classified into two categories: missing data and mutations